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Auditory nerve frequency tuning measured with forward-masked compound action potentials
(2012)
Frequency selectivity is a fundamental cochlear property. Recent studies using otoacoustic emissions and psychophysical forward masking suggest that frequency selectivity is sharper in human than in common laboratory ...
Stronger efferent suppression of cochlear neural potentials by contralateral acoustic stimulation in awake than in anesthetized chinchilla
(Frontiers Research Foundation, 2015)
© 2015 Aedo, Tapia, Pavez, Elgueda, Delano and Robles.There are two types of sensory cells in the mammalian cochlea, inner hair cells, which make synaptic contact with auditory-nerve afferent fibers, and outer hair cells ...
Frequency tuning of mechanical responses in the mammalian cochlea
(1996)
The search for mechanisms responsible for the high sensitivity and sharp frequency tuning of first-order auditory neurons has produced surprising results. The cochlea, the mammalian auditory receptor, responds to acoustic ...
Cochlear hair cells: The sound-sensing machines
(Elsevier, 2015-08-31)
The sensory epithelium of the mammalian inner ear contains two types of mechanosensory cells:inner (IHC) and outer hair cells (OHC). They both transduce mechanical force generated by soundwaves into electrical signals. In ...
Short-term plasticity and modulation of synaptic transmission at mammalian inhibitory cholinergic olivocochlear synapses
(Frontiers, 2014-12-02)
The organ of Corti, the mammalian sensory epithelium of the inner ear, has two types of mechanoreceptor cells, inner hair cells (IHCs) and outer hair cells (OHCs). In this sensory epithelium, vibrations produced by sound ...
Adaptive evolution in mammalian proteins involved in cochlear outer hair cell electromotility
(Academic Press Inc Elsevier Science, 2006-12)
Somatic electromotility in cochlear outer hair cells, as the basis for cochlear amplification, is a mammalian novelty and it is largely dependent upon rapid cell length changes proposed to be mediated by the motor-protein ...
Synaptic contributions to cochlear outer hair cell Ca2+ dynamics
(Society for Neuroscience, 2021-08)
For normal cochlear function, outer hair cells (OHCs) require a precise control of intracellular Ca21 levels. In the absence of regulatory elements such as proteinaceous buffers or extrusion pumps, OHCs degenerate, leading ...
The role of activity of the dorsal cochlear nucleus in tinnitus perception in mice
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM NEUROCIÊNCIAS, 2020-03-27)
Noise-induced tinnitus is the perception of an acute or chronic phantom sound, without a physical source, caused by over-exposure to loud noise. Tinnitus patients that report
bothersome tinnitus often suffer from increased ...
Encoding sound in the cochlea: from receptor potential to afferent discharge
(Wiley Blackwell Publishing, Inc, 2021-05)
Ribbon-class synapses in the ear achieve analog to digital transformation of a continuously graded membrane potential to all-or-none spikes. In mammals, several auditory nerve fibres (ANFs) carry information from each inner ...
Visualization of the mechanosensory machinery in live mammalian auditory hair cells
(Universidad Nacional de ColombiaMedellín - Ciencias - Maestría en Ciencias - BiotecnologíaEscuela de biocienciasFacultad de CienciasMedellínUniversidad Nacional de Colombia - Sede Medellín, 2021)
The inner ear detects sound-induced vibrations through deflection of rigid projections at the apex of mechanosensory hair cells, known as stereocilia. Stereocilia of a hair cell form the “hair bundle”. Sound is detected ...